Fun with strings! Ukulele, knitting, physics!
So abused kids grow up to have smaller hippocampi, but not every person with a small hippocampus also has major depression?
I’m gonna be really shallow and judgmental and just say her picture is creepy, too. What a bizarre pose and expression.
Does the company that bought Osprey still honor the warranty?
Keen Newports have the finger loops on tongue and heel. I think Blundstone boots do, too? I’m sure someone with Blundstones can confirm or refute that.
Those loops are so handy, I agree.
Bicycle. No gas expenses, no tabs, no loan, free parking. I understand how it works and can mostly fix it myself for very little money. I can take quiet side streets and arrive in a much better mood, plus my fat lazy ass gets some exercise.
This is the cool part:
But histotripsy foils cancer’s cloaking efforts by destroying its cell walls, leaving the tumor antigens in plain sight for the body’s immune system.
This effect was detailed in a pair of papers published by the U-M research team between March 2022 and January 2023. They demonstrate that the sound waves used to break down cancerous tumors in rats also helped trigger the rats’ immune response. After histotripsy destroyed 50% to 75% of liver tumor volume, the rats’ immune systems cleared away the rest, with no evidence of recurrence or metastases in more than 80% of animals.
That immune response occurred throughout the body, not just in areas targeted by the histotripsy treatment, resulting in the reduction of tumors far from the treated area.
The immune response is key. Without it, histotripsy is just yet another way to destroy a tumor without curing the cancer.
There have been similar studies looking at “feeding” mannose to solid tumors. The starve-the-tumor-with-fake-nutrients option has a lot of potential.
Not sure I want my neighbor pawing through my mail, or “accidentally” losing my ballot, or borrowing” my packages.
Privacy and security in the mail is crucial.
People are people. Human nature isn’t going to change just because the culture shifts to solarpunk.
Coffee makes me incredibly hungry (any caffeine does). This would backfire on me soooooo bad.
I have to wonder if an extra cup of any liquid per day would help avoid weight gain. You hear so much about people misinterpreting thirst as hunger - they eat instead of drinking.
Something like the Forest Schools and outdoor schools/daycares now. Students outdoors and engaging with the real world and each other nearly all the time. Nothing stripped to dry and abstract isolated bits (and boring) but always learning concepts in context and seeing how they interact.
I’m finding the opposite. Books that I loved when younger are even better as I re-read them now. Ursula le Guin, Terry Pratchett (their YA and their adult books) have so much more nuance and subtlety than I was aware of when I just read them for the adventure and story. There are some profound bits of wisdom and wry observation tucked in those books.
These are the same folks who think that the pinnacle of comedy is farting as you leave a crowded room.
You can add pockets to the pants you buy, too. This video by Morgan Donner is adding several examples of types of pockets to skirts, but the process is the same. https://www.youtube.com/watch?v=7pE_nrHKd58
And there’s this one by Bernadette Banner https://www.youtube.com/watch?v=thlzJj1EHiY
Thigh pockets are really great for phones. You can make visible patch pockets or subtle welt pockets and you can customize to the size of your phone.
Billy Connolly
300+ days a year of sunshine, all they need to do next is pop some solar panels up on those roofs!
You can rent a furnished studio short-term for 2 days minimum at $99/day, and you get the same transportation benefits as residents do during your stay. Honestly, I’m considering this for a vacation during the winter. This walkable community idea is fascinating to me and I want to check it out. https://culdesac.com/
For t shirts I always sing the praises of Gettees. Tiny “factory” of half a dozen people making extraordinarily high quality and durable shirts in Detroit. Most of the people doing the sewing are former auto upholstery stitchers from the car factories. The quality is truly the best I’ve ever encountered. https://gettees.us/
Side note about pockets: Duluth Trading women’s pants have multiple ginormous pockets, and about half have crotch gussets or anterior inseams to avoid chub-rub destroying the pants.
A “final solution”, as it were.
Are you talking about internal hubs? There are many bikes with internal hubs available in the US, far more than bikes with Pinions. Even department/sports stores like REI sell bikes with internal hubs. I have 4 bikes with internal hubs, one is a CVT which is a hoot to shift but heavy as heck.